DNA Structure and Replication Review!

DNA Structure and Replication Review!

DNA Structure and Replication Review! Test Multiple Choice, Matching, Short Answer What does DNA stand for? DeoxyriboNucleic

Acid BE COMFY WITH THE CORRECT SPELLING! ! What is the sugar named in DNA?

DEOXYRIBOSE 5-Carbon sugar In the DNA Double Helix, the sugar is bonded to what molecule? Phosphate

group Follow up question what is the bond that holds the sugar and phosphate together?!? Covalent bonds

Phosphate and sugar are bonded together. What is then bonded to the sugar molecule? Nitrogenous Base Name the 4 nitrogenous bases.

1. Adenine 2. Guanine 3. Cytosine 4. Thymine are bonded together by what type of bond? This holds the 2 strands together.

Hydrogen bond Tell me the difference. Purine Pyrimidin e Tell me the difference.

Purine Pyrimidine Adenine Guanine 2 Ring Structure Thymine

Cytosine 1 Ring Structure What nitrogenous bases pair together? Adenine Thymine Guanine Cytosine Purine Pyrimidines!!

This scientist used X-ray diffraction to find information about DNA. Found that DNA is in the shape of a helix or a coiled spring. Rosalind Franklin

DNA is in the shape of a double helix (twisted ladder). These Scientists realized that the double helix accounted for Franklins Xray pattern, and it explained Chargaffs rule of base pairing and how the 2 strands of DNA are held together. This 3D model can even tell us how DNA can function as a carrier of genetic information

James Watson & Francis Crick Define Chargaffs Rule the amounts of adenine and thymine are almost always equal, as are the amounts of guanine and cytosine.

Fill in the chart! Adenin Thymin Guanin Cytosin e e e e % of Each Base

Pair 38% Fill in the chart! Adenin Thymin Guanin Cytosin e e e e

% of Each Base Pair 12% 12% 38%

38% Automatically you should know that Cytosine will be the same as Guanine. 38+38 = 76% 100-76= 24 Adenine and Thymine = 24 Total 24/2 = 12% each Tell me the general

steps of DNA Replication 1 2 3 4

DNA Unwinds and Unzips Helix unwinds and 2 DNA strands separate at the Hydrogen bonds between nitrogen bases DNA Polyermase helps to link free floating DNA nucleotides with complimentary nucleotides on each of the two strands Covalent bonds join nucleotides above and below each other on the new strands.

Hydrogen bonds join complimentary base pairs Each new DNA MOLECULE formed contains One parent strand and a new strand present in the first step of DNA replication DNA HELICASE! HINT THINK STRUCTURE

HELIX (UNWIND & UNZIP) What ENZYME is present to bring free nucleotides to the form the new strand of DNA . DNA polymerase

What are the two strands referred to as in the process of Replication? Parent Strand (original) New/Daughter Strand (copied) What happens when an error is made in the

replication process? MUTATION Where is DNA found in a PROKARYOTIC cell? CYTOPLASM o Remember they do not have organelles do not have a nucleus!!! DONE!

Study o Note Packet o Scientist WS/Movie o Genome WS o HW Worksheets o All PowerPoints o Email if you have any questions

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